SP690COMPLEMENT AND CONTACT SYSTEM ACTIVATION DURING HEMODIALYSIS
نویسندگان
چکیده
منابع مشابه
[Activation of complement during hemodialysis].
In hemodialysis using 3 types of dialysis membrane materials [regenerated cellulose (RC), cellulose triacetate (CTA), and polysulfone (PS)], activation of the complement, reduction of white blood cells, and variation of vitronectin (VN) were observed. RC membrane caused a significant reduction of white blood cells and elevations of Bb and soluble membrane attack complex (S-MAC), indicating a st...
متن کاملPhysiologic activities of the contact activation system.
The plasma contact activation (CAS) and kallikrein/kinin (KKS) systems consist of 4 proteins: factor XII, prekallikrein, high molecular weight kininogen, and the bradykinin B2 receptor. Murine genetic deletion of factor XII (F12(-/-)), prekallikrein (Klkb1(-/-)), high molecular weight kininogen (Kgn1(-/-)) and the bradykinin B2 receptor (Bdkrb2(-/-)) yield animals protected from thrombosis. Wit...
متن کاملLack of clinically significant contact system activation during platelet concentrate filtration by leukocyte removal filters.
When blood (plasma) contacts certain foreign surfaces, factor XII can activate and trigger a series of reactions leading to cleavage of kininogens with subsequent release of bradykinin. In this study, we investigated two different widely used leukocyte removal filters, Pall PXL8K (A) and Asahi PLS-5A (B), to test whether clinically significant contact activation occurred during leukodepletion o...
متن کاملMechanisms of CDC-42 activation during contact-induced cell polarization.
Polarization of early embryos provides a foundation to execute essential patterning and morphogenetic events. In Caenorhabditis elegans, cell contacts polarize early embryos along their radial axis by excluding the cortical polarity protein PAR-6 from sites of cell contact, thereby restricting PAR-6 to contact-free cell surfaces. Radial polarization requires the cortically enriched Rho GTPase C...
متن کاملDuring contact activation of plasma, cleavage of surface-bound Hageman
During contact activation of plasma, cleavage of surface-bound Hageman factor (HF) 1 occurs at two closely situated sites, one within a disulfide loop, termed "site 1", and one outside the disulfide loop, termed "site 2" (1). The result of these cleavages is two forms of active HF (2) which we have given the names a-HF a and fi-HFa. Fig. 1 defines these two forms based on their derivation (last...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2017
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfx155.sp690